Cartilage Mechanics and Tissue Engineering Laboratory

Lori A. Setton, Ph.D.

BME Department Pratt Duke Ortho

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Welcome to the Setton and Chen Laboratory

Research in the Laboratory is focused on understanding the mechanisms for degeneration and regeneration of soft tissues of the musculoskeletal system, including the intervertebral disc, articular cartilage, and meniscus.

Our research interests include:

  • Intervertebral Disc and Cartilage Tissue Engineering
  • Stem Cells for Regenerative Medicine
  • Drug Delivery
  • Cell and Extracellular Matrix Biomechanics
  • Animal Gait and Behavior in Models of Pain

News Brief

  • November 2011 - The Laboratory presented a broad array of papers at this year's meeting of the North Carolina Tissue Engineering and Regenerative Medicine Society. Congratulations go to Timothy Mwangi, who won Best Poster Presentation for his work entitled, "Silk Fibroin Microparticles for Intra-articular Drug Delivery of Curcumin."

  • October 2011 - Laboratory members, Dovina Qu and Esther Lee, presented their research at the 2011 Annual Meeting of the BMES in Hartford this week. Dr. Robby Bowles presented work on engineering education that he studied while at Cornell, and Dr. Kyle Allen (Florida) presented on his work studying rodent gait in animal models performed while he was at Duke. Go to the Photos tab to see BMES 2011 photos.

  • September 2011 - Congratulations to Michael on the successful presentation of his preliminary proposal on sustained release strategies for the delivery of curcumin.

  • September 2011 - Priscilla Hwang has learned that she was awarded the Mort Friedman Departmental Fellowship from the Biomedical Engineering Department at Duke. A much deserved honor for Priscilla!

  • August 2011 - Dr. Jun Chen and Dana Nettles are excited to receive a grant from the North Carolina Biotechnology Center to study translational applications of modified silks for cartilage repair. They will work with a broad set of collaborators to achieve their goals. Good luck!


  • Copyright © 2011 Lori Setton
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